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2002 Accepted Abstracts
This list includes invited abstracts, those accepted for oral presentation and those
accepted for poster presentation.
MITOCHONDRIAL DNA DELETION MUTATIONS AND SARCOPENIA
Judd Aiken
AGE-RELATED LOSS OF FACILITATING CORTICOSTRIATAL SYNAPSES MAY BE RELATED TO AN INTERACTION BETWEEN STRIATAL DOPAMINE AND REACTIVE OXYGEN SPECIES
G. Akopain, C. Crawford, L. Yang L., M.F. Beal, Walsh J.P.
Differential Responses to Oxidative Stress in the Brain of Normal Aged Humans Versus Alzheimer's Disease
A.C. Andorn, P.C. Bickford, D. Hogan
Planarians As Animal Models For Comparative Biogerontology: A Prospectus
R.M. Anson
The Protective Effects of Dietary Restriction Can be Dissociated From Calorie Intake
R. Michael Anson, Zhihong Guo, Rafael de Cabo, Titilola Iyun, Michelle Rios, Adrienne Hagepanos, Donald K. Ingram, Mark P. Mattson, Mark A. Lane
SCOPOLAMINE IMPAIRS VISUO-SPATIAL WORKING MEMORY IN AN AGE-DEPENDENT MANNER.
J.A. Araujo, A.D.F. Chan, C. Mascella, N.W. Milgram
AMYLOID PRECURSOR PROTEIN AND ACTIVATION OF MICROGLIA
S.W. Barger, S-Z. Wu, A.M. Bodles, A.S. Basile
THE AGING HIPPOCAMPUS, MOLECULES, MAPS, AND MEMORY IN RATS AND NON-HUMAN PRIMATES
C.A. Barnes
QUANTITATIVE LONGITUDINAL ANALYSIS OF MITOCHONDRIAL DNA DELETION MUTATIONS IN ELECTRON TRANSPORT SYSTEM ABNORMAL REGIONS
M. Bassiouni, A. Herbst, J.M. Aiken
Teaching an Old Rat New Tricks: Cerebellar Motor Learning
Paula C. Bickford
MITOCHONDRIAL ROLE IN AGE-RELATED RESPONSES OF NEURONS TO A-BETA AND GLUTAMATE
Gregory J. Brewer, John R. Torricelli, Nicole Capps, Jason Nash
Unifying Mechanism of Estrogen-Induced Neuroprotection
Roberta Diaz Brinton and Jon Nilsen
PROGRESSION OF SARCOPENIA AND ASSOCIATED ELECTRON TRANSPORT SYSTEM ABNORMALITIES
E. A. Bua, S. H. McKiernan, M. Speleos and J. M. Aiken
PHYSICAL PERFORMANCE IN AGED RATS PREDICTS LONGEVITY: IMPLICATIONS FOR ASSESSING PRECLINICAL INTERVENTIONS
C.S. Carter, G. Onder, W.E. Sonntag, M. Pahor
MODULATION OF HIPPOCAMPAL NEUROGENESIS BY BLUEBERRY DIETARY SUPPLEMENTATION
Gemma Casadesus, Barbara Shukitt-Hale, Heather M. Stellwagen, and James A. Joseph
Effects of Growth Hormone Resistance on Gene Expression: Studies in GHR-KO (Laron Dwarf) mice
K Cochran, M J Iqbal, B Bailey, and A Bartke
Plasma Membrane Redox System During Aging and Caloric Restriction
R de Cabo, C Gilman, M Garcia, G Lopez, M Mattson, M Anson, P Navas and Mark A. Lane
Development of Model Systems to Assess the Role of Estrogens in Neuroprotection
Darlene C. Deecher and Istvan Merchenthaler
A natural model of population heterogeneity fits observed mortality distributions, including their tail
A.D.N.J. de Grey
Mechanisms of Associative Learning in Young and Aging Hippocampus
John F. Disterhoft
LINK BETWEEN AGING CLOCK AND MORTALITY RATE: RELIABILITY APPROACH
S. Doubal, P. Klemera
GENOTYPE AND AGE INFLUENCE THE EFFECT OF CALORIC RESTRICTION ON MORTALITY
M.J. FORSTER, N. SUMIEN, P. MORRIS, R.S. SOHAL
Flow Chart of Biochemical Interactions Causing Human Aging
J.D. Furber
EAT LESS OR EAT BLUEBERRIES: RESTORING HSP70 NEUROPROTECTION IN THE
R.L. Galli, D. Bielinski, A. Szprengiel, B.Shukitt-Hale, J.A. Joseph
Exercise, Learning and the Aging Brain
W. T. Greenough, J. Churchill, R. Galvez
DELAYING BRAIN MITOCHONDRIAL DECAY WITH MITOCHONDRIAL ANTIOXIDANTS/METABOLITES, ACETYL-L-CARNITINE AND R-a-LIPOIC ACID IN OLD RATS
J Liu, E. Head, A Gharib, C. W. Cotman, and B. N. Ames,
Characterization of long-lived wild-derived house mice (Mus musculus)
J.M. Harper, R.A. Miller
CAN AN OLD BIRD BE TAUGHT NEW TRICKS? TELOMERE LENGTH INCREASES WITH AGE IN A LONG-LIVED BIRD.
M.F. Haussmann, D.W. Winkler, K.M. O'Reilly, C.M. Vleck
Assessment of learning in rhesus monkeys on long-term calorie restriction
D. Ingram, J. Young, E. Hanson, M. Murray, G. Roth, M. Lane
Free radical-dependent bcl-2/NFkB interactions in the aged CNS
J. Kaufman, M. Thomas. C. Massaad, P. Bickford, G. Taglialatela
GENE EXPRESSION PROFILING OF AGING AND CALORIC RESTRICTION ON THE
Tsuyoshi Kayo, Tomas A Prolla and Richard Weindruch
Peroxide Treatment Induces Upregulated Apoptosis in the Ames Dwarf Mouse
M.A. Kennedy, S.G. Rakoczy, H.M. Brown-Borg
Preservation of cognitive and motor function in middle-aged animals: Implications for the role of growth hormone in aging
B.A. Kinney, N.E. Kinney, K.T. Coschigano, J.J. Kopchick, R.W. Steger, A. Bartke
TETRAHYDROCURCUMIN PROLONGS SURVIVAL CURVES OF MALE C57BL MICE
K.Kitani, T. Osawa
Cell-by-Cell analysis of mtDNA Mutations and the Mitochondrial Theory of Aging
Y. Kraytsberg, E. Nekhaeva, N. B. Bodyak and K. Khrapko
EFFECT OF AGE AND ESTRADIOL ON FINE MOTOR SKILLS IN FEMALE RHESUS MONKEYS
A. Lacreuse, J.G. Herndon
INFLAMMATORY MECHANISMS IN ALZHEIMER'S DISEASE: MICROGLIAL SIGNALING AND TRANSCRIPTIONAL REGULATION
G. Landreth, C. Combs, C. Karlo and S. Sundararajan
MITOCHONDRIAL METABOLITES, ACETYL-L-CARNITINE AND LIPOIC ACID, IMPROVE AGE-ASSOCIATED MEMORY DECLINE AND INHIBIT BRAIN OXIDATIVE DAMAGE IN OLD RATS
J. Liu, A. Gharib, E. Head, C. W. Cotman, and B. N. Ames
IMPAIRMENT IN SYNAPTIC PLASTICITY IN THE RAT HIPPOCAMPUS CAN BE REVERSED BY DIETARY MANIPULATION: A ROLE FOR INTERLEUKIN-1
MA Lynch
REGIONAL DIFFERENCES IN AGE-RELATED CHANGES IN NMDA RECEPTOR EXPRESSION WITHIN THE PREFRONTAL CORTEX AND HIPPOCAMPUS
K.R. Magnusson, L. Bai, D. Kresge, and J. Supon
ULTRASTRUCTURAL CHANGES IN SKELETAL MUSCLE OF POSTMENOPAUSAL WOMEN FOLLOWING TWELVE MONTHS OF AEROBIC EXERCISE AND PROGRESSIVE RESISTANCE TRAINING
Cosmas, A.C., Monteiro, M., Levesque, S., Fiataroni-Singh, M., Manfredi, T.G.
MEASURING RESPONSE TIME WITH AN ERROR OF 1% OR LESS AND RELIABILITY OF 0.96:
R. Martin, R. Coppings, K.E. Gerstmann, W. Holmes, A. Kokesh, D. Mathew, C. Pappas, A. Pruchnicki, B. Sachs, R. Schnoll, A. Wetherell
THE CHINESE-AMERICAN LONGEVITY STUDY
R. Martin, R. Schnoll, A. Pruchnicki, R. Rambadt
The influence of sodium intake on cardiovascular endpoints in rhesus monkeys
J.A. Mattison, H. Spurgeon, P. Pullen, E.G. Lakatta, D.K. Ingram, G.R. Roth, M.A. Lane
Does Caloric Restriction Affect Electron Transport System Abnormalities?
S. H. McKiernan, E. A. Bua and J. M. Aiken
Mitochondrial Oxidative Stress and Therapeutics
S.L. Melov
NSAIDS-INDUCED REVERSAL OF AGE-RELATED DEFICITS IN LEARNING AND MEMORY: POSSIBLE INVOLVEMENT OF PRO-INFLAMMATORY CYTOKINES
M.H. Mesches, C. Gemma, L.M. Veng, C. Allgeiers, M.D. Browning, and P.C. Bickford
PRESERVATION OF COGNITIVE FUNCTION IN AGED CANINES: COLLABORATIVE EFFECTS OF AN ANTIOXIDANT ENRICHED DIET AND COGNITIVE EXPERIENCE
Milgram NW, Head EH, Zicker S, Muggenberg B, Cotman, CW
INFLAMMATORY MECHANISMS IN BRAIN AGING. POSSIBLE SITES FOR INTERVENTION
D. Morgan
CR may be able to improve maintenance of naive T-cells in old Rhesus Macaques
Janko Nikolich-Zugich
Brain gene expression is modified by Gingko biloba extract EGb 761 and in a-tocopherol deficient mice
Kishorchandra Gohil and Lester Packer
POINT MUTATIONS IN RAT MUSCLE AND HEART mtDNA
J. W. Pak, F. Vang, and J. M. Aiken
Inhibition of Expressions of Matrix Metalloproteinase-1 and Growth Factors in Mammary and Endometrial Cells by Estrogen, Progesterone or/and Prolactin
Neena Philips, Karyn McFadden, Jennifer Stellatella, Jennifer Monteleone and Courtney Hurley
GENERATION OF MITOCHONDRIAL HSP70 TRANSGENIC MICE
Radhika Puttagunta and Tomas Prolla
SKELETAL MUSCLE ANTIOXIDANT DEFENSE AND OXIDATIVE STRESS IN EXERCISE-TRAINED AGING-DELAYED AMES DWARF MICE
M.A. Romanick, S.G. Rakoczy, H.M. Brown-Borg
Age-related changes in cognition and the brain of the Rhesus monkey: evidence for inflammatory processes in white matter
M.A. Romanick, S.G. Rakoczy, H.M. Brown-Borg
GLYCOLYSIS AND GLUCOREGULATION AS TARGETS FOR CALORIE RESTRICTION MIMETICS
G.S. Roth, M.A. Lane, J.A. Mattison, D.K.Ingram
AGE-RELATED WORKING MEMORY DEFICITS DETECTED IN MICE PERFORMING WATER MAZE TASKS
B. Scruggs, J. Aniya, K.C. Wright, and K.R. Magnusson
EFFECTS OF MELATONIN AND ACETYL L-CARNITINE ON BIOCHEMICAL AND BEHAVIORAL PARAMETERS OF BRAIN AGING
E. H. Sharman, N. D. Vaziri, Z. Ni, K. G. Sharman, S. C. Bondy
Structure-Neuroprotective Activity Relationships Among Estrogens and Related Molecules
J.W. Simpkins, S.H. Yang, R. Liu, Y. Wen, D.G. Watson, E.J. Perez, T. Fan, and A.L. Day
SIGNALING OXIDATIVE STRESS IN ALZHEIMER DISEASE
Xiongwei Zhu, Osamu Ogawa, Craig S. Atwood, George Perry, Mark A. Smith
Role of Mitochondria in the aging process
R.S. Sohal
ESTROGEN EFFECTS ON SEPTAL CHOLINERGIC NEURONS IN CULTURE
J. Stoll, C. Martin, C. Hoelting
Effects of Tumor Necrosis Factor-alpha on the Expression of Inducible Nitric Oxide Synthase in Nerve Growth Factor-Responsive Pheochromocytoma Cells
M.S. Thomas, W.R. Zhang, A.C. Andorn, G. Taglialatela
Altered methionine metabolism in long living Ames dwarf mice
E.O. Uthus and H.M. Brown-Borg
Genotoxicity of Electron Transport Inhibitors: Models of Neurodegenerative Diseases.
B. Van Houten, B.Mandavilli, J.Santos, L. Hunakova and Y. Chen.
ANALYSIS OF CHANGES IN MITOCHONDRIAL PROTEINS WITH AGE IN WILDTYPE AND MNSOD KNOCKOUT MICE
H. Van Remmen, J. Chang, T. Shibatani, W. Ward, J. E. Cornell and A. Richardson
AGE-RELATED INCREASE IN L-TYPE CALCIUM CHANNEL PROTEIN IN THE HIPPOCAMPUS CORELATES WITH SPATIAL WORKING MEMORY IMPAIRMENT
L. M. Veng, M.H. Mesches, M.D. Browning
PARALLELS IN COGNITIVE FUNCTION OF AGED MONKEYS AND HUMANS
M.L. Voytko
THE INFLUENCE OF AGE AND GENDER UPON THE EFFECTS OF CHRONIC NEUROINFLAMMATION
G.L. Wenk, L. Marriott, B. Hauss-Wegrzyniak
Oxidative Damage and the Mitochondrial Membrane in Age-related Cataract
N.S. Wolf, W.R. Pendergrass, P.E. Penn, G.M. Martin, H. VanRemmen
PARALLELS IN AGE-RELATED CHANGES IN LEARNING AND THE CEREBELLUM
D. S. Woodruff-Pak
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