American Aging Association - 35th Annual Meeting
Interventions in Aging and Age-related Diseases: The Present and the Future 

June 2-5, 2006  Boston, MA, USA

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35th ANNUAL MEETING PROGRAM

Interventions in Aging and Age-related Diseases: The Present and the Future

June 2 - 5, 2006

Boston, MA - USA

Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University

(click here for a print version)

 

FRIDAY, JUNE 2, 2006
PRE-MEETING SYMPOSIUM: Calorie Restriction

Organizer: Richard Weindruch

7:00 AM Registration and Continental Breakfast at Jean Mayer USDA-HNRCA at Tufts University - located at 711 Washington Avenue (one block from the Marriott Courtyard Tremont Hotel)  
8:00 Welcome Richard Weindruch
8:05 Model organisms
  SIR2 Genes and Calorie Restriction Leonard P. Guarente
  A Biochemical/Genetic Pathway for the Life Span Extending Effects of Calorie Restriction in the Fly Stephen L. Helfand
  Dietary Restriction and Gene Expression in C. elegans David Gems
  Calorie Restriction in Yeast and Worms: Public or Private Mechanisms Matt Kaeberlein
10:05 Break  
10:20 Rodents
  Effects of Moderate (8%) Caloric Restriction on Free Radical Biology Chris Leeuwenburgh
 

Metabolic Regulators in Calorie Restriction: Linking Cell Survival and Organismal Longevity

Rozalyn M. Anderson
11:20 Lunch Break
12:30 PM Non-human primates
  The University of Wisconsin Dietary Restriction and Aging Study Ricki Colman
  The NIA Study of Dietary Restriction and Aging Donald K. Ingram
  Delay in T-Cell Senescence by Caloric Restriction in Aged Long-Lived Non-Human Primates Janko Nikolich-Zugich
2:00 Break
2:15 Human primates
  Long-term Adaptations to CR John O. Holloszy
  Feasibility of Long-Term Caloric Restriction in Humans Susan B. Roberts
  Effect of CR on Energy Metabolism with Emphasis on Mitochondrial Biogenesis Eric Ravussin
 

Panel Discussion: Is Caloric Restriction the Only Way to Increase Health Span?

Moderator: James Joseph

Panelists: Eric Ravussin and Stephen R. Spindler

5:00-7:00

AGE CONFERENCE REGISTRATION (AT COURTYARD MARRIOTT)

5:00-7:00 AGE BOARD MEETING (AT COURTYARD MARRIOTT)
7:00-9:00

Welcome Reception (AT COURTYARD MARRIOTT)

35th AGE ANNUAL MEETING

Interventions in Aging and Age-related Diseases: The Present and the Future

SATURDAY, JUNE 3

7:00 AM Registration and Continental Breakfast at Jean Mayer USDA-HNRCA at Tufts University - located at 711 Washington Avenue (one block from the Marriott Courtyard Tremont Hotel)
8:15 Welcome Notes Simin Meydani, Chair
8:30

SESSION 1: Current Advances in Understanding the Basic Biology of Aging

CHAIR: Raj Sohal

 

Identification of Mechanisms of Aging from Worm to Man

Siegfried Hekimi

 

Reactive Oxygen Species, Signal Transduction and Aging

Toren Finkel

 

Mitochondrial Respiratory Activity, Oxidative Stress & Aging

Raj Sohal

10:15 Break
10:30

SESSION 2: Sarcopenia: Cause, Effect, and Treatment

CHAIR: William Evans

 

Molecular Mechanisms in Relation to Sarcopenia

Geoff Goldspink

 

Hormonal and Pharmacological Treatment

Shalender Bhasin

 

Nutritional and Exercise Interventions

William J. Evans

  Effect of Protein Intake on Change in Muscle Strength in Older Persons: Does Inflammation Matter? Benedetta Bartali (N*)
  Tourniquet-Induced Ischemia/Reperfusion Damage in Aging Skeletal Muscle Roger Farrar
12:30 PM - 2:00 PM

NEW!  Lunch and AGE sponsored debate:  Amyloid-beta and Alzheimer's Disease:  Center Ring or Side Show? - Moderator: Dr. Donald Ingram; Debaters: Drs. Benjamin Wolozin and Mark A. Smith

2:00

SESSION 3:  Osteoporosis: Mechanisms, Prevention and Treatments

CHAIR: Connie Weaver

 
Osteoporosis: In Search of an Underlying Mechanism 

Robert Klein

 

Osteoporosis: Life Choices for Prevention

Connie Weaver

 

Osteoporosis:  Treatments, but No Cure

Dennis Black

3:30-5:30

Poster session – Wine and Cheese Reception

Competition for the Nicolai Prize and the Glenn Award

6:00 SOCIAL (Dinner and Dance Cruise) - reservation required; bus departs 6pm from Tufts University
35th AGE ANNUAL MEETING - SUNDAY, JUNE 4
7:00 AM Registration and Continental Breakfast at Jean Mayer USDA-HNRCA at Tufts University
8:15

SESSION 4: Intervention in Aging and Age-Related Skin Diseases

CHAIR: Barbara Gilchrest

The Role of Telomere-Based Signaling in Skin Aging/Photoaging Mina Yaar
 

The Role of Retinoids in Preventing and Treating Skin Aging Changes

Sewon Kang

 

Mechanisms and Consequences of Age-Associated Changes in the Skin Barrier

Peter Elias

9:45 Break
10:00

SESSION 5: Immunity and Infection

Session Supported by the Ellison Medical Foundation

CHAIR: Laura Haynes

  Age and the Adaptive Immune System Jorg Goronzy
 
The Effect of Age on the Cognate Function of CD4 T- Cells 
Laura Haynes
 

Influenza Vaccination: T-Cell Responses Translate to Health Outcomes in Older Adults

Janet E. McElhaney
  Vitamin E Supplementation Reverses the Age Associated Decline in Phosphorylation of the Adaptor Protein LAT in CD4+ T Cells of Old Mice Melissa Marko (N*)
  Regulation of T-Cell Responses to Acute and Cronic Viruses in Old Rodents Janko Nikolich-Zugich
12:00 PM – 2:00 PM

Luncheon - Annual Awards (AT COURTYARD MARRIOTT)

  • Distinguished Achievement Award

  • Harman Research Award

  • Hayflick Award

  • Journalism Awards

  • Nicolai and Glenn Awards

Keynote Speaker: Britton Chance - Cognitive function evaluated by NIR spectroscopy

2:00

SESSION 6: Trans-Atlantic Awareness & Collaboration Symposium on Aging Research - sponsored by the Biotechnology and Biological Sciences Research Council (BBSRC) through the UK SPARC Network for Ageing Research

CHAIRS: Richard Faragher and Norman Wolf
  The Modification of IL-7 and the Reversal of Thymic Atrophy in Aged Mice Sian Hansen
  Functional Effect of Failure of Adaptive Responses in Skeletal Muscle During Aging Anne McArdle
  Reconstructing Young and Aged Skin Ian Kill
  Analyzing the Relationship Between Oxidative Stress and Aging in Drosophila Robert Saunders
  Understanding Soft Tissue Aging - the Effect of Cyclical Loading Roger Smith
  Inclusive Design Tool Based on Psychological and Biomechanical Functional Performance Bernie Conway
4:00 Break
4:15–5:15 Denham Harman Lecture: Philip W. Landfield  
5:15-6:15

AGE BUSINESS MEETING

6:30 Student Session (CHAIR: Rafael de Cabo)
  • Data Blitz
  • Round Table - discussion on perspectives on careers in aging research for young scientists
  • Social event
35th AGE ANNUAL MEETING - MONDAY, JUNE 5     
7:00 AM Registration and Continental Breakfast at Jean Mayer USDA-HNRCA at Tufts University
8:15

SESSION 7: Metabolic Syndrome and Aging

CHAIRS: Mohsen Meydani and Jose Ordovas

 

Adipocytes, Inflammation and the Metabolic Syndrome in Aging

Nir Barzilai

  Obesity, Regional Body Fat Distribution and the Metabolic Syndrome in Older Men and Women Tamara Harris
 

Intervention in Metabolic Syndrome of Aging

Jose Ordovas
 

SIRT1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic Beta-Cells

Laura Bordone

  Aging Up-Regulates Expression of Inflammatory Mediators in Mouse Adipose Tissue Dayong Wu
10:15 Break
10:30 HAYFLICK AWARD LECTURE: Kenichi Kitani - WHAT REALLY DECLINES WITH AGE? Kenichi Kitani
11:15

SESSION 8: Calcium-Mediated Signal Transduction in Brain Aging

Session Supported by the Ellison Medical Foundation

CHAIR: James Joseph

 

The  Duality of  Signaling  Effects  Induced by  Dietary  Interventions in Oxidative Stress or Learning Paradigms

James Joseph

 

Relationships among Signaling Proteins, Age, and Memory

Paul J. Colombo

 

Therapeutic Targets in Alzheimer's Disease: Signal Transduction Mechanisms

Mark A. Smith

12:30 PM - 2:00 PM

NEW! Lunch – Trans-Atlantic Collaboration on Aging Workshop

Moderated by: Simin Meydani, Richard Faragher and Norman Wolf

2:15-4:15

NEW! PUBLIC SESSION -  A New Age for Aging

CHAIR: Miriam E. Nelson

Co-Chair: Simin Meydani

  Strong Women and Men Live Well: an Update on Physical Activity and Aging Miriam E. Nelson
  Supplements for Health - Should I Take and Which Ones? Irwin H. Rosenberg
  Positive Emotions and Aging James Goodwin

*N - Pre-doctoral candidate for the Nicolai Prize

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