| A memorial fund has been established to honor our Executive Director Dr. Mark Smith. To learn more about Dr. Smith and his career, please visit the following sites and read the recollections of his collaborators and students (below).
In addition to his scientific achievements (see his "top" papers below), Mark received two teaching (mentoring) awards, served as Executive Director of the American Aging Association and as the chief and final decision-maker for the Association's fundraising action group. He also served as co-Editor-in-Chief of the Journal of Azheimer's Disease and on the editorial board of our Journal of the American Aging Association and other journals.
The Mark Smith Memorial Fund will be used to support free radical and Alzheimer's disease-related presentations at our annual meetings and will bear Mark's name on the program and award certificate. This award is to support participation of one or more promising trainees at the AGE Annual Meeting and to encourage students to maintain the scientific and personal standards that made Mark so special. All contributions are tax deductible.
To make a donation to this award, please click the link below. Thank you.
Mark's Recommendations
This section of his memorial page is under development. Mark recommended that all members of the American Aging Association place their profiles on ResearchID.com, as he has done, so that the full impact of this Association's members can be tallied and better appreciated. He noted that maintaining an up-to-date ResearchID profile can help each investigator's career as well as organizational goals. Mark's advice to collaborators and students, which undoubtedly helped earn him his two mentoring awards, will be added as feedback is received.
If you were a student or collaborator of Mark's, and recall his advice to you, please let us know by clicking here. Thank you in advance. Please leave your email address if you wish to be notified when significant updates to this page have been made.
Mark's Most-Cited Publications (from his Alzforum profile)
- Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci. 1997 Apr 15;17(8):2653-7. PMID: 9092586 (627 citations - now automatically updated at ResearcherID.com to 743)
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Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem. 1997 May;68(5):2092-7.PMID: 9109537 (455 citations - now automatically updated at ResearcherID.com to 575)
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Smith MA, Taneda S, Richey PL, Miyata S, Yan SD, Stern D, Sayre LM, Monnier VM, Perry G. Advanced Maillard reaction end products are associated with Alzheimer disease pathology. Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5710-4. PMID: 8202552 (445 citations)
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Smith MA, Perry G, Richey PL, Sayre LM, Anderson VE, Beal MF, Kowall N. Oxidative damage in Alzheimer's. Nature. 1996 Jul 11;382(6587):120-1. PMID: 8700201 (434 citations)
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Smith MA, Harris PL, Sayre LM, Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9866-8. PMID: 9275217 (375 citations)
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Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Aug;60(8):759-67. PMID: 11487050 (342 citations)
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Yan SD, Chen X, Schmidt AM, Brett J, Godman G, Zou YS, Scott CW, Caputo C, Frappier T, Smith MA, et al. Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress.
Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7787-91. PMID: 8052661 (339 citations)
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Smith MA, Sayre LM, Monnier VM, Perry G. Radical AGEing in Alzheimer's disease. Trends Neurosci. 1995 Apr;18(4):172-6. PMID: 7778188 (303 citations)
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Smith MA, Hirai K, Hsiao K, Pappolla MA, Harris PL, Siedlak SL, Tabaton M, Perry G. Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress. J Neurochem. 1998 May;70(5):2212-5. PMID: 9572310 (265 citations)
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Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci. 1999 Mar 15;19(6):1959-64. PMID: 10066249 (244 citations)
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